Allsphere Silica is a high-purity, fully porous HPLC column with an unmodified silica surface, ideal for traditional normal-phase and adsorption chromatography. The accessible silanol groups enable strong polar interactions, such as hydrogen bonding and dipole-dipole interactions, making this phase well-suited for the separation of polar compounds, isomers, and neutral organic molecules. Allsphere Silica is a robust option for method development and classical retention mechanisms.
Allsphere Silica provides strong polar selectivity and reproducible performance – ideal for laboratories using normal-phase or adsorption-based chromatography.
Bare silica (USP L3) for normal-phase and adsorption mode
Strong polar interactions via free silanol groups
High surface area and well-controlled particle morphology
Suitable for non-polar solvents such as hexane, heptane, and isopropanol
Available in 3 µm, 5 µm and 10 µm particle sizes
Separation of polar organics, structural isomers, and lipids
Classical normal-phase HPLC methods
Adsorption chromatography and dry-loading techniques
Retention profiling in method development for polar compounds
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Surface Area | 220 m²/g |
| Phase/Modification | Si |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| Carbonload | 0 % |
| Phase | Material Number |
|---|---|
| Allsphere Silica, 3 µm | 5203039 |
| Allsphere Silica, 5 µm | 5203040 |
| Allsphere Silica, 10 µm | 5203041 |