Brava CN-BDS is a cyanopropyl-modified HPLC column based on high-purity, fully porous silica, featuring base deactivation (Base Deactivated Silica) for improved peak shape and reduced silanol interactions. This phase offers dual-mode selectivity, making it suitable for both reversed-phase and normal-phase chromatography. Brava CN-BDS is especially effective for separating polar and aromatic compounds, positional isomers, and analytes with dipole-interaction potential.
Brava CN-BDS provides flexible, base-deactivated selectivity for polar and aromatic compounds – ideal for dual-mode chromatography and complex method development.
Cyanopropyl (CN) bonded phase with base deactivation (USP L10)
Applicable in both reversed-phase and normal-phase modes
Enhanced selectivity for polar and aromatic compounds
Reduced silanol activity for better peak symmetry
Available in 3 µm, 5 µm, and 10 µm particle sizes
Polar pharmaceuticals and aromatic analytes
Normal-phase separations of neutral compounds
Structural isomer resolution
Method development requiring alternative retention mechanisms
| Particle Sizes |
|
|---|---|
| Pore Size | 145 Å |
| Surface Area | 180 m²/g |
| Phase/Modification | CN |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 5 % |
| Phase | Material Number |
|---|---|
| Brava CN-BDS, 3 µm | 5204023 |
| Brava CN-BDS, 5 µm | 5204024 |
| Brava CN-BDS, 10 µm | 5204025 |