Brava Silica is a high-purity, fully porous HPLC column with an unbonded silica surface, specifically designed for normal-phase and adsorption-based separations. Its active silanol groups provide strong polar interactions, such as hydrogen bonding and dipole-dipole retention, making it ideal for the separation of polar compounds, isomers, and neutral organics. Brava Silica is robust, reproducible, and suitable for classical chromatography workflows using non-polar eluents.
Brava Silica offers classical silica retention for polar compound separations – ideal for laboratories applying traditional normal-phase or adsorption techniques.
Bare silica phase (USP L3) for normal-phase applications
Strong silanol activity for polar retention mechanisms
High surface area and pore structure for adsorption separations
Compatible with non-polar solvents (e.g. hexane or heptane)
Available in 3 µm, 5 µm and 10 µm particle sizes
Separation of polar compounds and structural isomers
Normal-phase chromatography of lipids, fats, and neutral organics
Dry-loading and preparative method development
Adsorption and polarity-based method optimization
| Particle Sizes |
|
|---|---|
| Pore Size | 130 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | Si |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| Carbonload | 0 % |
| Phase | Material Number |
|---|---|
| Brava Silica, 3 µm | 5204032 |
| Brava Silica, 5 µm | 5204033 |
| Brava Silica, 10 µm | 5204034 |