CT-Sil Diol

Polar HPLC Phase for Normal-Phase and HILIC Separations

CT-Sil Diol is a diol-functionalized HPLC column based on fully porous, high-purity silica, designed for normal-phase and HILIC (hydrophilic interaction liquid chromatography) applications. The diol groups provide moderate polarity and enable hydrogen bonding and dipole-dipole interactions, offering a less active alternative to bare silica with improved reproducibility and milder retention behavior.

This phase is particularly useful for separating polar compounds, sugars, and isomers, and is compatible with non-polar as well as aqueous-organic mobile phases.

CT-Sil Diol offers controlled polar retention and broad compatibility – a dependable choice for laboratories working with polar analytes in normal-phase or HILIC mode.

Key Features

  • Diol-bonded phase for normal-phase and HILIC chromatography

  • Lower surface activity than bare silica for improved reproducibility

  • Suitable for polar and hydrophilic analytes

  • Fully porous silica for stable and efficient separations

  • Available in 5 µm

Typical Applications

  • Sugar and carbohydrate separations

  • Polar drug compounds and metabolites

  • Normal-phase separations in organic solvents

  • HILIC separations in acetonitrile-rich mobile phases

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 100 Å
Surface Area 200 m²/g
Phase/Modification Diol
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 0 %

Material Number

Phase Material Number
CT-Sil Diol, 5 µm ct15.d0.
CT-Sil CN

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