Econosphere Cyano

Dual-Mode HPLC Column for Polar and Aromatic Compound Separation

Econosphere Cyano is a cyanopropyl-modified HPLC column based on fully porous, high-purity silica, designed for use in both reversed-phase and normal-phase chromatography. The cyano functional group provides moderate polarity and dipole-dipole interaction, enabling selective retention of polar, aromatic, and structurally related compounds. This versatile column offers cost-efficient performance for method development and routine analysis.

Econosphere Cyano is a flexible and affordable choice for dual-mode HPLC – ideal for separating polar and aromatic compounds in routine analytical workflows.

Key Features

  • Cyanopropyl (CN) bonded phase – USP L10 classification

  • Suitable for reversed-phase and normal-phase separations

  • Polar selectivity with reduced hydrophobic retention

  • Fully porous silica with stable, reproducible behavior

  • Available in 3 µm, 5 µm and 10 µm particle sizes

Typical Applications

  • Polar drug substances and aromatic analytes

  • Normal-phase separations of neutral organics

  • Method development for isomeric or moderately polar compounds

  • General-purpose chromatography in pharmaceutical and food analysis

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Surface Area 200 m²/g
Phase/Modification CN
Particle Type
Separation Modes
USP Code
Endcapping Yes
Carbonload 6 %

Material Numbers

Phase Material Number
Econosphere Cyano, 3 µm 5205010
Econosphere Cyano, 5 µm 5205011
Econosphere Cyano, 10 µm 5205011
Econosphere C18 Econosphere Silica

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