EcoPrep 60 C18-2 NE

Preparative C18 Column with Neutral Endcapping for Scalable Small Molecule Purification

EcoPrep 60 C18-2 NE is a preparative reversed-phase HPLC column packed with fully porous, high-purity silica featuring a 60 Å pore size and bonded with C18 chains. This configuration provides strong hydrophobic retention, improved peak symmetry, and reduced silanol interaction, making it ideal for the purification of small non-polar and moderately polar molecules.

The column is optimized for high-throughput preparative workflows, offering excellent scalability, reproducibility, and loading capacity in pharmaceutical and chemical production.

EcoPrep 60 C18-2 NE offers robust and scalable reversed-phase purification – ideal for small molecule workflows requiring consistent performance and high efficiency.

Key Features

  • C18-bonded silica with 60 Å pore size

  • Strong reversed-phase retention and reduced silanol activity

  • Designed for preparative purification of small molecules

  • Fully porous silica with excellent mechanical stability

  • Available in 50 µm particle size

Typical Applications

  • Preparative purification of APIs and synthetic intermediates

  • Fractionation of hydrophobic compounds in R&D and production

  • Scale-up of analytical methods for process development

  • Cost-effective compound isolation in pharmaceutical environments

Specifications

Request Product
Particle Size
  • 50 µm
Pore Size 60 Å
Surface Area 550 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping No
Carbonload 32 %
pH Range 2 to 8

Material Number

Phase Material Number
EcoPrep 60 C18-2 NE, 50 µm 6136959
EcoPrep 60 Si

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info@dr-maisch.com +49 7073 5035 7

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