Equisil Gold C18

High-Purity Reversed-Phase Column for Precise and Reproducible Separations

Equisil Gold C18 is a reversed-phase HPLC column based on ultra-high purity, fully porous silica, bonded with octadecyl groups and optimized for high-efficiency separations. With advanced surface treatment and full endcapping, this column delivers excellent peak shape, low silanol activity, and strong hydrophobic retention, making it ideal for demanding applications in pharmaceutical, chemical, and bioanalytical workflows. Equisil Gold C18 ensures high reproducibility, even with challenging basic or polar analytes, and is well suited for use in validated and regulated environments.

Equisil Gold C18 combines premium silica quality with high-performance bonding – the ideal column for precise, reproducible reversed-phase HPLC separations.

Key Features

  • Octadecyl (C18) bonded phase – USP L1 classification

  • Ultra-high purity silica with advanced bonding chemistry

  • Full endcapping for reduced silanol interaction and improved peak symmetry

  • Strong hydrophobic retention with excellent lot-to-lot reproducibility

  • Available in 3 µm, 5 µm, and 10 µm particle sizes

Typical Applications

  • Pharmaceutical impurity profiling and method validation

  • Separation of basic and polar compounds

  • Complex formulation analysis and bioanalytical methods

  • Robust reversed-phase separations in regulated environments

Specifications

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Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 175 Å
Surface Area 220 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 14 %
pH Range 2 to 8

Material Numbers

Phase Material Number
Equisil Gold C18, 3 µm e23.9g.
Equisil Gold C18, 5 µm e25.9g.
Equisil Gold C18, 10 µm e20.9g.
Equisil Gold C8

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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