Equisil CPS

Reversed-Phase HPLC Column with Cyano Selectivity for Moderate Polarity Separations

Equisil CPS is a high-performance HPLC column featuring a cyano-bonded stationary phase on fully porous, high-purity silica. The cyano phase provides moderate hydrophobicity combined with polar interaction capabilities, enabling fast and selective separations of moderately polar compounds, structural isomers, and analytes with limited retention on standard C18 columns. Equisil CPS offers excellent peak symmetry, short analysis times, and broad solvent compatibility, making it ideal for reversed-phase and polar normal-phase applications in routine and regulated environments.

Equisil CPS from offers versatile cyano selectivity – ideal for analytical HPLC methods requiring short run times, orthogonal selectivity, or enhanced resolution of polar analytes.

Key Features

  • Cyano-bonded silica (USP L10) for dual-mode retention

  • Moderate hydrophobicity with polar interaction selectivity

  • Suitable for both reversed-phase and normal-phase conditions

  • Fully porous high-purity silica for high reproducibility

Typical Applications

  • Fast separations of moderately polar compounds

  • Separation of positional isomers and aromatic analytes

  • Reversed-phase HPLC with low-organic gradients

  • Normal-phase LC of polar compounds using non-polar solvents

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 120 Å
Surface Area 180 m²/g
Phase/Modification CN
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 5 %
pH Range 2 to 8

Material Number

Phase Material Number
Equisil CPS, 5 µm e25.c0.
Equisil APS-2 Equisil CPS-2

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