Equisorb ODS-2 is a reversed-phase HPLC column packed with fully porous, high-purity silica particles bonded with octadecyl chains and additionally endcapped to reduce residual silanol activity. This results in improved peak symmetry and greater retention stability, especially for basic or polar analytes. Compared to ODS-1, Equisorb ODS-2 offers reduced tailing and enhanced reproducibility, making it ideal for method validation, routine analysis, and pharmaceutical quality control.
Equisorb ODS-2 is a robust and reliable C18 column – ideal for high-precision reversed-phase HPLC applications requiring consistent performance and improved chromatographic behavior.
Endcapped C18 reversed-phase silica – USP L1
Strong hydrophobic retention with reduced silanol interactions
Improved peak shape and reproducibility for basic compounds
Suitable for isocratic and gradient elution
Fully porous high-purity silica with batch-to-batch consistency
Available in 3 µm, 5 µm and 10 µm particle sizes
Analysis of APIs and drug-related impurities
Routine reversed-phase HPLC in pharmaceutical QC
Method development with focus on peak shape optimization
Separation of non-polar to moderately polar analytes
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Surface Area | 220 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 18 % |
| Phase | Material Number |
|---|---|
| Equisorb ODS-2, 3 µm | e03.92. |
| Equisorb ODS-2, 5 µm | e05.92. |
| Equisorb ODS-2, 10 µm | e00.92. |