Equisorb SCX

Strong Cation Exchange HPLC Column for Basic and Positively Charged Compounds

Equisorb SCX is a strong cation exchange HPLC column packed with fully porous, high-purity silica particles functionalized with sulfonic acid groups. This phase provides strong ionic interactions with positively charged analytes, enabling efficient separation of basic compounds such as amines, alkaloids, and peptides. The column offers excellent reproducibility, strong retention of cationic species, and compatibility with aqueous buffer systems across a wide pH range, making it suitable for ion-exchange chromatography in pharmaceutical, environmental, and bioanalytical applications.

Equisorb SCX offers strong and reliable ion-exchange performance – ideal for separations requiring high selectivity for cationic analytes in complex sample matrices.

Key Features:

  • Strong cation exchange phase with sulfonic acid groups – USP L9

  • Selective retention of basic and positively charged analytes

  • Fully porous high-purity silica for robust and reproducible performance

  • Compatible with aqueous buffers in a broad pH range

  • Ideal for method development and routine analysis

Typical Applications:

  • Separation of amines, basic drugs, and alkaloids

  • Ion-exchange chromatography of peptides and metabolites

  • Bioanalytical workflows involving cationic species

  • Environmental and pharmaceutical testing

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 80 Å
Surface Area 220 m²/g
Phase/Modification SCX
Particle Type
Separation Mode
USP Code
Endcapping No
Carbonload 10 %

Material Numbers

Phase Material Number
Equisorb SCX, 3 µm e03.sc.
Equisorb SCX, 5 µm e05.sc.
Equisorb SCX, 10 µm e00.sc.
Equisorb SAX Equisorb Si

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info@dr-maisch.com +49 7073 5035 7

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