Exsil 80 ODS-1

C18 Silica Phase with Controlled Hydrophobicity for Reversed-Phase HPLC

Exsil 80 ODS-1 is a silica-based HPLC stationary phase with an 80 Å pore size and an octadecyl (C18, ODS-1) bonded surface engineered for controlled hydrophobic retention in reversed-phase HPLC. Compared to high-carbon-load C18 phases, ODS-1 provides moderate retention strength, enabling improved selectivity and shorter analysis times for small molecules.

The optimized surface coverage and high surface area support sharp peak shapes, high chromatographic efficiency, and reproducible retention behavior, making Exsil 80 ODS-1 suitable for both routine analysis and method development.

Exsil 80 ODS-1 delivers balanced hydrophobic retention, high efficiency, and reliable reproducibility, making it an effective solution for controlled reversed-phase HPLC separations of small molecules.

Key Features:

  • Silica-based HPLC stationary phase with 80 Å pore size

  • Octadecyl (C18, ODS-1) bonded phase with controlled hydrophobicity

  • Moderate retention strength compared to high-load C18 phases

  • High efficiency and reproducible chromatographic performance

  • Optimized for small-molecule reversed-phase HPLC

  • Available particle sizes: 3 µm, 5 µm, 10 µm

Typical Applications:

  • Reversed-phase separation of low-molecular-weight pharmaceuticals

  • Analysis of compounds requiring reduced C18 retention

  • Method development with fine-tuned hydrophobic selectivity

  • Faster HPLC methods compared to high-carbon-load ODS phases

  • Food, environmental, and chemical analysis

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 80 Å
Surface Area 220 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes

Material Numbers

Phase Material Number
Exsil 80 ODS-1, 3 µm 5136485.
Exsil 80 ODS-1, 5 µm 5136498.
Exsil 80 ODS-1, 10 µm 5136506.
Exsil 80 ODS Exsil 80 Phenyl

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