Exsil Avanti BDS Si

Base-Deactivated Bare Silica for Controlled Normal-Phase and HILIC Separations

Exsil Avanti BDS Si is a high-purity base-deactivated bare silica stationary phase designed for advanced normal-phase chromatography, adsorption chromatography, and HILIC applications. Built on the proven Avanti BDS platform, this material combines the strong polar selectivity of unmodified silica with reduced silanol activity for improved peak symmetry and reproducibility.

The base-deactivation process minimizes uncontrolled secondary interactions while preserving the intrinsic adsorption characteristics of silica. As a result, Exsil Avanti BDS Si provides controlled polar retention, sharper peak shapes, and more predictable chromatographic behavior, particularly for polar, multifunctional, and structurally related analytes. The highly purified spherical silica matrix ensures excellent mechanical stability, uniform packing quality, and consistent performance under both HPLC and UHPLC conditions. The phase is compatible with traditional normal-phase solvent systems as well as aqueous-organic eluents used in hydrophilic interaction chromatography (HILIC).

Exsil Avanti BDS Si combines the selectivity of high-purity silica with advanced base-deactivation technology—delivering reliable, controlled, and high-resolution separations for polar and adsorption-driven chromatographic methods.

Key Features

  • Base-deactivated bare silica

  • Controlled polar selectivity with reduced silanol activity

  • Improved peak symmetry compared to conventional silica

  • High efficiency and reproducible retention behavior

  • Robust spherical silica for HPLC and UHPLC use

  • Suitable for normal-phase and HILIC workflows

Typical Applications

  • Normal-phase separation of polar compounds

  • HILIC analysis of highly hydrophilic analytes

  • Isomer and structural variant separations

  • Pharmaceutical and chemical method development

  • Adsorption-based chromatographic applications

Specifications

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Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 145 Å
Surface Area 185 m²/g
Phase/Modification Si
Particle Type
Separation Mode
USP Code
Endcapping No
Carbonload 0 %
pH Range 2 - 8

Material Numbers

Phase Material Number
Exsil Avanti BDS Si, 3 µm 6136944
Exsil Avanti BDS Si, 5 µm 6136880.
Exsil Avanti BDS Si, 10 µm 6136988.
Exsil Avanti BDS QUATTRO

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