GreatSmart Silica

Unmodified Silica HPLC Column for Normal-Phase and Adsorption Chromatography

GreatSmart Silica is an HPLC column packed with fully porous, high-purity bare silica particles. This unbonded phase provides strong polar interactions and adsorption capacity, making it ideal for normal-phase chromatography, polar compound separations, and planar isomer resolution. The column is compatible with non-polar solvents such as hexane, heptane, and chloroform, and is well-suited for use in industrial, pharmaceutical, and academic laboratories requiring basic and cost-effective normal-phase separations.

GreatSmart Silica offers reliable normal-phase performance – a robust, economical choice for adsorption-based HPLC workflows.

Key Features:

  • Bare silica stationary phase – USP L3

  • Strong retention of polar and hydrogen-bonding analytes

  • Ideal for normal-phase and adsorption-based separations

  • Fully porous, high-purity silica with reproducible performance

  • Available in 3 µm, 5 µm and 10 µm particle sizes

Typical Applications:

  • Normal-phase separations of polar organics and small molecules

  • Retention of positional and geometric isomers

  • Sample cleanup and fractionation in non-aqueous systems

  • HPLC training and basic method development

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 120 Å
Surface Area 230 m²/g
Phase/Modification Si
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 0 %

Material Numbers

Phase Material Number
GreatSmart Silica, 3 µm 5212028
GreatSmart Silica, 5 µm 5212029
GreatSmart Silica, 10 µm 5212030
GreatSmart RP18

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

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