GromSil 100 ODS-2 FE is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with fully porous, high-purity silica with a 100 Å pore size and bonded with octadecyl (C18) ligands. The phase features full endcapping (FE), effectively masking residual silanol groups to minimize secondary interactions. This results in excellent peak symmetry, reduced tailing, and highly reproducible retention — especially for basic and ionizable compounds.
The column is ideal for pharmaceutical and chemical analysis where precision, robustness, and regulatory compliance are essential.
Offering high stability and consistent retention, the fully endcapped C18 phase from Dr. Maisch HPLC GmbH is well suited for demanding reversed-phase HPLC applications in regulated and research environments.
Octadecyl (C18) bonded reversed-phase phase with full endcapping – USP L1
Fully porous silica with 100 Å pore size
Suppressed silanol activity for enhanced peak shape and reproducibility
Strong hydrophobic retention suitable for a broad analyte range
Available in 3 µm, 5 µm, and 10 µm particle sizes
Basic drug substances and pharmaceutical impurities
LC-MS and UV-based reversed-phase method development
Robust quality control and validated analytical procedures
General-purpose separations with high column efficiency
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 100 ODS-2 FE, 3 µm | GSOD20310. |
| GromSil 100 ODS-2 FE, 5 µm | GSOD20510. |
| GromSil 100 ODS-2 FE, 7 µm | GSOD20710. |