GromSil 100 SCX is a strong cation exchange (SCX) HPLC column from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with a 100 Å pore size and functionalized with sulfonic acid groups. This phase provides strong and stable electrostatic interaction with positively charged analytes such as amines, basic drug substances, peptides, and other cationic species.
It is ideal for salt gradient or isocratic ion-exchange separations and is compatible with aqueous buffer systems used in pharmaceutical, biochemical, and environmental analysis.
With its stable retention and robust exchange capacity, this SCX phase from Dr. Maisch HPLC GmbH is ideal for reliable separation of basic and positively charged analytes in modern ion-exchange chromatography.
Strong cation exchange phase with sulfonic acid functionality – USP L17
Fully porous silica with 100 Å pore size
High selectivity and strong retention of basic and cationic analytes
Compatible with aqueous buffer systems and LC-MS workflows
Available in 5 µm and 10 µm particle sizes
Amines, basic pharmaceuticals, peptides, and bioactive amine compounds
Ion-exchange separations under acidic to neutral pH conditions
Method development for cationic drug substances
Analytical and preparative workflows requiring strong cation selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Phase/Modification | SCX |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 100 SCX, 5 µm | GSSC10510. |
| GromSil 100 SCX, 10 µm | GSSC11010. |