GromSil 120 Octyl-6 MB is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with a 120 Å pore size and bonded with octyl (C8) ligands. The MB (modern bonding) surface modification ensures efficient endcapping and a deactivated silanol surface, resulting in excellent peak symmetry and reproducibility—especially for basic and polar analytes.
Offering moderate hydrophobic retention, this phase is ideal for compounds that elute too slowly on C18 columns, and it enables flexible method development across a wide polarity range.
Combining selectivity and efficiency, GromSil 120 Octyl-6 MB from Dr. Maisch HPLC GmbH is a versatile reversed-phase column – ideal for analytical workflows that require robust performance and excellent peak shape across a broad range of analytes.
Octyl (C8) bonded reversed-phase phase with modern endcapping – USP L7
Fully porous silica with 120 Å pore size
High column efficiency and sharp peak shape
Reduced silanol activity for improved performance with basic compounds
Available in 3 µm, 5 µm, and 10 µm particle sizes
Basic drug substances, polar APIs, and medium-hydrophobic molecules
LC-MS and UV detection in pharmaceutical and chemical analysis
Method development requiring moderate retention and reproducibility
Screening of compounds with diverse polarity profiles
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 120 Octyl-6 MB, 3 µm | GSOC60312. |
| GromSil 120 Octyl-6 MB, 5 µm | GSOC60512. |