GromSil 120 ODS-6 NE is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with fully porous, high-purity silica (120 Å pore size) and bonded with octadecyl (C18) ligands. The non-endcapped (NE) surface preserves free silanol groups, enabling enhanced secondary interactions such as hydrogen bonding and weak ion exchange. This makes it particularly suitable for basic, polar, and ionizable analytes that may elute too early or show limited retention on fully endcapped phases.
Its orthogonal selectivity is valuable for method development, selectivity scouting, and the separation of closely related compounds.
With its increased polar interaction potential, GromSil 120 ODS-6 NE from Dr. Maisch HPLC GmbH is an ideal choice for reversed-phase separations requiring greater selectivity and interaction diversity.
Octadecyl (C18) bonded reversed-phase phase – USP L1 classification
Fully porous silica with 120 Å pore size
Non-endcapped surface for increased silanol interaction
Enhanced selectivity for polar, basic, and ionizable analytes
Available in 3 µm, 5 µm, and 10 µm particle sizes
Basic pharmaceuticals, polar small molecules, and isomers
Selectivity screening and orthogonal method development
Retention enhancement for weakly retained analytes
LC-MS and UV detection with polar mobile phase systems
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 120 ODS-6 NE, 3 µm | GSOD60312. |
| GromSil 120 ODS-6 NE, 5 µm | GSOD60512. |
| GromSil 120 ODS-6 NE, 10 µm | GSOD61012. |