GromSil 120 TMS-1 ST is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on high-purity, fully porous silica with a 120 Å pore size and modified with trimethylsilyl (TMS) groups. This short-chain alkyl phase provides very weak hydrophobic interaction, allowing fast elution of highly lipophilic or sterically hindered analytes that are overly retained on standard C18 or C8 phases.
The TMS modification also minimizes secondary polar interactions, making this column ideal for method development where low retention and minimal surface activity are required.
With its uniquely mild retention profile, GromSil 120 TMS-1 ST from Dr. Maisch HPLC GmbH is the ideal choice for fast and selective separations of compounds that challenge conventional reversed-phase columns.
Trimethylsilyl (C1) bonded reversed-phase phase – USP L13 classification
Fully porous silica with 120 Å pore size
Very low hydrophobic retention for fast elution
Reduced surface activity for improved peak shape of sensitive compounds
Available in 3 µm, 5 µm, and 10 µm particle sizes
Highly hydrophobic or bulky molecules
Early eluting compounds in rapid gradient LC
Method development requiring minimal retention strength
Orthogonal selectivity to C18/C8 phases
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Phase/Modification | TMS (C1) |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 120 TMS-1 ST, 3 µm | GSTM10312. |
| GromSil 120 TMS-1 ST, 5 µm | GSTM10512. |