GromSil 80 SCX is a strong cation exchange (SCX) HPLC column from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with an 80 Å pore size and functionalized with sulfonic acid groups. The phase provides strong electrostatic interactions with positively charged analytes such as amines, basic pharmaceuticals, and peptides.
Its stable surface chemistry and high exchange capacity make it ideal for analytical and preparative applications involving salt gradients or isocratic separations in aqueous buffer systems.
With reliable ion-exchange performance and robust chemical stability, GromSil 80 SCX from Dr. Maisch HPLC GmbH is an excellent choice for reversed-phase–orthogonal separations of basic and cationic compounds in analytical and preparative HPLC.
Strong cation exchange phase with sulfonic acid functionality – USP L17 classification
Fully porous silica with 80 Å pore size
Strong retention of basic and protonated compounds
Compatible with aqueous mobile phases and buffer systems
Available in 5 µm and 10 µm particle sizes
Separation of amines, basic drug substances, and peptides
Ion-exchange chromatography in pharmaceutical and biochemical workflows
Method development involving positively charged analytes
LC-MS and UV detection of cationic species
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Phase/Modification | SCX |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 80 SCX, 3 µm | GSSC10308. |
| GromSil 80 SCX, 5 µm | GSSC10508. |
| GromSil 80 SCX, 10 µm | GSSC11008. |