Hypergrom ODS

Core-Shell C18 Column for Fast and High-Resolution Reversed-Phase Separations

Hypergrom ODS is a high-efficiency reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with advanced core-shell particles bonded with octadecyl (C18) ligands. This phase offers strong hydrophobic retention, excellent peak shape, and high efficiency—ideal for rapid separations and high-throughput applications without sacrificing resolution.

Thanks to the solid core and porous shell particle design, this column delivers reduced band broadening and lower backpressure compared to fully porous materials, enabling fast separations on both UHPLC and conventional HPLC systems.

With its optimized C18 chemistry and core-shell particle design, Hypergrom ODS from Dr. Maisch HPLC GmbH is a powerful tool for fast, precise, and reproducible reversed-phase separations.

Good alternative to Hypersil™ ODS (Thermo Scientific™).

Key Features:

  • C18 bonded reversed-phase phase – USP L1 classification

  • Core-shell silica particles for high efficiency and low backpressure

  • Strong hydrophobic retention and sharp peak shape

  • Compatible with LC-MS and UV detection

  • Available in 2.6 µm and other sub-3 µm particle sizes

Typical Applications:

  • Fast separation of APIs, impurities, and degradation products

  • LC-MS and UV workflows in pharmaceutical and bioanalytical analysis

  • Method development requiring high resolution and short run times

  • Routine QC and high-throughput reversed-phase applications

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Particle Type
Separation Mode
USP Code
Endcapping Yes
pH Range 2 - 8

Material Numbers

Phase Material Number
Hypergrom ODS, 3 µm HGOD10312.
Hypergrom ODS, 5 µm HGOD10512.

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

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