Macrosphere 60 SEC is a silica-based stationary phase specifically engineered for aqueous size exclusion chromatography (SEC) in the molecular weight range of 250 to 28,000 Daltons. The phase is built on high-purity spherical silica with a 60 Å pore size and features a hydrophilic diol surface modification, ensuring accurate size-based separations of small biomolecules and water-soluble polymers.
The diol functionalization forms a stable, hydrophilic surface that minimizes secondary interactions between analytes and the silica matrix, resulting in pure size-exclusion behavior. This design provides high resolution and reproducibility for the separation of peptides, oligosaccharides, small biopolymers, and other low-molecular-weight compounds. With its excellent mechanical stability, consistent calibration behavior, and long operational lifetime, Macrosphere 60 SEC is ideally suited for analytical and preparative use in biochemical, pharmaceutical, and biotechnological applications.
Macrosphere 60 SEC combines a hydrophilic diol-modified surface with precision-engineered silica – the reliable choice for accurate and reproducible aqueous SEC separations in the 250 to 28,000 Dalton range.
Silica-based stationary phase with 60 Å pore size and diol surface modification
Designed for aqueous SEC separations between 250 and 28,000 Da
Hydrophilic surface minimizes adsorption and secondary interactions
High mechanical stability and reproducibility for long column lifetime
Suitable for analytical and preparative workflows
Available particle size: 5 µm
Molecular weight determination of peptides, oligosaccharides, and small biopolymers
Separation of water-soluble compounds in biochemical and pharmaceutical research
Characterization of low-molecular-weight biomolecules in aqueous SEC
Quality control and method development in life science laboratories
| Particle Size |
|
|---|---|
| Pore Size | 60 Å |
| Phase/Modification | Diol |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| Phase | Material Number |
|---|---|
| Macrosphere 60 SEC, 5 µm | ms05.sec. |