Platinum 300 C8-EPS is a silica-based HPLC stationary phase with an octyl bonded surface and a 300 Å pore size, developed for the reversed-phase separation of biomolecules such as peptides, proteins, and other high-molecular-weight compounds. The EPS (Extended Polar Selectivity) design introduces controlled residual silanol activity, enhancing interactions with polar sites of analytes and providing superior selectivity for complex biomolecular separations.
Unlike fully endcapped C8 materials, Platinum 300 C8-EPS is not endcapped, offering a carefully balanced combination of hydrophobic and polar retention. This enables improved resolution for analytes containing both polar and nonpolar functional groups, while maintaining excellent peak shapes and reproducibility. The large 300 Å pore structure ensures optimal accessibility and mass transfer for macromolecules, making this phase ideal for biopharmaceutical and proteomic applications. Built on high-purity, mechanically robust silica, Platinum 300 C8-EPS provides reliable performance, long column lifetime, and consistent results even under demanding gradient conditions.
Platinum 300 C8-EPS delivers the perfect balance between hydrophobic retention and polar selectivity – the dependable choice for accurate and reproducible biomolecular separations in reversed-phase HPLC.
Silica-based stationary phase with C8 bonding and 300 Å pore size
Not endcapped – engineered for extended polar selectivity (EPS)
Balanced hydrophobic and polar retention behavior
Optimized for peptides, proteins, and other biomolecules
High-purity silica ensures robustness, reproducibility, and long lifetime
Available particle sizes: 3 µm, 5 µm
Reversed-phase separation of peptides and proteins
Analysis of biomolecules and biopharmaceutical products
Method development requiring both polar and hydrophobic selectivity
Quality control and research in pharmaceutical and life science laboratories
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Surface Area | 100 m²/g |
| Phase/Modification | C8-EPS |
| Particle Type | |
| Separation Mode | |
| USP Codes | |
| Endcapping | No |
| Phase | Material Number |
|---|---|
| Platinum 300 C8-EPS, 3 µm | 5136694 |
| Platinum 300 C8-EPS, 5 µm | 5136695 |