ReproKrom C18

Standard Reversed-Phase HPLC Column for Robust Small Molecule Analysis

ReproKrom C18 is a silica-based HPLC column with an octadecyl bonded phase, engineered for strong hydrophobic retention, reproducibility, and robustness. As the most widely used stationary phase in reversed-phase chromatography, it provides reliable separations across a broad range of small molecule analytes. Built on high-purity silica with durable bonding chemistry, ReproKrom C18 ensures sharp peak shapes, long operational lifetimes, and consistent results under routine and demanding chromatographic conditions. It is a dependable choice for pharmaceutical, biochemical, food, and environmental applications.

ReproKrom C18 delivers proven C18 performance with reproducibility and robustness – the reliable choice for laboratories conducting reversed-phase HPLC separations of small molecules.

Key Features:

  • Silica-based stationary phase with octadecyl (C18) bonded chemistry

  • Strong hydrophobic retention for diverse small molecules

  • High reproducibility and sharp peak symmetry

  • Robust bonding ensures long column lifetime

  • Available particle sizes: 3.5 µm, 5 µm, 10 µm

Typical Applications:

  • Pharmaceutical impurity profiling and stability-indicating assays

  • Biochemical analysis of hydrophobic drugs and metabolites

  • Food and beverage testing for preservatives, additives, and contaminants

  • Environmental monitoring of hydrophobic organic pollutants

  • Method development requiring robust and reproducible C18 selectivity

Specifications

Request Product
Particle Sizes
  • 3.5 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Surface Area 300 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 20 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproKrom C18, 3.5 µm rk13.9e.
ReproKrom C18, 5 µm rk15.9e.
ReproKrom C18, 10 µm rk10.9e.
ReproKrom C8 ReproKrom Si

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