ReproSil Fluosil 100 PFP

Pentafluorophenyl Column for Unique Selectivity in Small-Molecule HPLC

ReproSil Fluosil 100 PFP from Dr. Maisch HPLC GmbH is a high-purity silica HPLC column with a 100 Å pore size and a pentafluorophenyl bonded phase. This fluorinated aromatic phase provides multiple interaction mechanisms, including π–π interactions, dipole–dipole interactions, and hydrogen bonding, enabling unique selectivity for aromatic, polar, and halogenated compounds. The 100 Å pore size offers high surface area for small-molecule analysis, delivering sharp peaks, high resolution, and excellent reproducibility for both isocratic and gradient methods.

ReproSil Fluosil 100 PFP columns from Dr. Maisch HPLC GmbH deliver unique fluorinated aromatic selectivity – the perfect choice for challenging small-molecule HPLC separations.

Key Features:

  • Fully porous, ultra-pure silica with 100 Å pore size

  • Pentafluorophenyl (PFP) bonding for multiple interaction mechanisms

  • Enhanced selectivity for aromatic, polar, and halogenated analytes

  • High efficiency and reproducibility for small-molecule separations

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available from 1.8 µm to 10 µm particle sizes

Typical Applications:

  • Separation of aromatic pharmaceuticals and intermediates

  • Analysis of halogenated compounds and positional isomers

  • Method development for polar and aromatic analytes

  • Complex mixture separations requiring orthogonal selectivity

Specifications

Request Product
Particle Sizes
  • 1.8 µm
  • 2 µm
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Surface Area 450 m²/g
Phase/Modification PFP
Particle Type
Separation Modes
USP Code
Endcapping Yes
Carbonload 12 %
pH Range 2 to 8

Applications

Material Numbers

Phase Material Number
ReproSil Fluosil 100 PFP, 1.8 µm fl118.pfp.
ReproSil Fluosil 100 PFP, 2 µm fl12.pfp.
ReproSil Fluosil 100 PFP, 3 µm fl13.pfp.
ReproSil Fluosil 100 PFP, 5 µm fl15.pfp.
ReproSil Fluosil 100 PFP, 10 µm fl10.pfp.
ReproSil Fluosil 60 PFP ReproSil Fluosil 120 PFP

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

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