ReproSil Gold 120 C4

Wide-Pore C4 Column for Gentle Separation of Proteins and Peptides

ReproSil Gold 120 C4 from Dr. Maisch HPLC GmbH is a high-purity silica HPLC column with a 120 Å pore size and a butyl bonded phase. The shorter alkyl chain provides lower hydrophobic retention compared to C18 or C8 phases, enabling mild elution conditions that help preserve the structure and activity of proteins, peptides, and other sensitive biomolecules. The wide-pore design ensures efficient mass transfer and optimal accessibility for medium to large analytes, while delivering sharp peaks, high resolution, and excellent reproducibility.

ReproSil Gold 120 C4 columns from Dr. Maisch HPLC GmbH deliver gentle, reproducible separations with wide-pore accessibility – the ideal choice for sensitive protein and peptide HPLC applications.

Key Features:

  • Fully porous, ultra-pure silica with 120 Å pore size

  • C4 bonding – USP L26 classification

  • Gentle hydrophobic retention for sensitive biomolecules

  • Optimized for peptides, small proteins, and biomolecules

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 3 µm, 5 µm, 10 µm, and 20 µm particle sizes

Typical Applications:

  • Protein and peptide separations under mild conditions

  • Biopharmaceutical QC and proteomics research

  • Gradient HPLC for medium-to-large hydrophobic biomolecules

  • Method development for labile analytes

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
  • 20 µm
Pore Size 120 Å
Surface Area 300 m²/g
Phase/Modification C4
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 8 %
pH Range 2 to 9

Material Numbers

Phase Material Number
ReproSil Gold 120 C4, 3 µm r13.4g.
ReproSil Gold 120 C4, 5 µm r15.4g.
ReproSil Gold 120 C4, 10 µm r10.4g.
ReproSil Gold 120 C4, 20 µm r120.4g.
ReproSil Gold 120 C2 ReproSil Gold 120 C8

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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