ReproSil pHoenix C18

High-pH Stable C18 Column for Robust Reversed-Phase Separations

ReproSil pHoenix C18 from Dr. Maisch HPLC GmbH is a high-purity silica-based HPLC column specifically engineered for high-pH stability in reversed-phase applications. Its octadecyl bonded phase is protected with a special surface modification that resists hydrolysis, enabling reliable operation in alkaline mobile phases up to pH 12. This makes it ideal for applications requiring improved selectivity for basic compounds, enhanced method flexibility, and extended column lifetime under harsh pH conditions, all while maintaining strong hydrophobic retention and high efficiency.

ReproSil pHoenix C18 columns from Dr. Maisch HPLC GmbH deliver robust, high-resolution performance under high-pH conditions – the optimal choice for demanding reversed-phase HPLC separations.

Key Features:

  • Fully porous, ultra-pure silica with pH-stable surface modification

  • C18 bonding – USP L1 classification

  • Stable in alkaline mobile phases up to pH 12

  • Strong hydrophobic retention with excellent reproducibility

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available from 1.5 µm to 10 µm particle sizes

Typical Applications:

  • High-pH separations of basic pharmaceuticals and metabolites

  • Method development requiring alkaline mobile phases

  • Improved selectivity for ionizable analytes

  • Long-lifetime reversed-phase HPLC in harsh conditions

Specifications

Request Product
Particle Sizes
  • 1.5 µm
  • 3 µm
  • 5 µm
  • 7 µm
  • 10 µm
Pore Size 100 Å
Surface Area 470 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 22 %
pH Range 1 to 12

Material Numbers

Phase Material Number
ReproSil pHoenix C18, 1.5 µm ph119.9e.
ReproSil pHoenix C18, 3 µm ph13.9e.
ReproSil pHoenix C18, 5 µm ph15.9e.
ReproSil pHoenix C18, 7 µm ph17.9e.
ReproSil pHoenix C18, 10 µm ph10.9e.

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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