ReproSil-Pur 60 Si

High-Purity Silica HPLC Column for Normal-Phase Separations

ReproSil-Pur 60 Si is an unbonded, high-purity silica HPLC column with a 60 Å pore size, optimized for normal-phase and adsorption chromatography of small molecules. The active silanol groups provide strong polar interactions, making it highly effective for analytes that are weakly retained on reversed-phase columns. The use of ultra-pure silica reduces secondary interactions, ensuring sharp peak shapes, reproducibility, and long operational lifetimes. ReproSil-Pur 60 Si is a versatile choice for pharmaceutical, chemical, and environmental laboratories requiring reliable normal-phase separations.

ReproSil-Pur 60 Si combines high-purity silica with robust polar selectivity – the dependable choice for laboratories performing normal-phase HPLC separations of small molecules.

Key Features:

  • Unbonded high-purity silica stationary phase

  • 60 Å pore size optimized for small molecule separations

  • Strong polar interactions for normal-phase chromatography

  • Excellent reproducibility with sharp and symmetrical peak shapes

  • Available particle sizes: 3 µm, 5 µm

Typical Applications:

  • Normal-phase separations of nonpolar and weakly polar compounds

  • Pharmaceutical impurity profiling and stability testing

  • Chemical and petrochemical analysis requiring polar selectivity

  • Environmental monitoring of nonpolar pollutants

  • Method development requiring orthogonal selectivity to reversed-phase HPLC

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 60 Å
Surface Area 450 m²/g
Phase/Modification Si
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 0 %
pH Range 2 to 8

Applications

Material Numbers

Phase Material Number
ReproSil-Pur 60 Si, 3 µm r03.04.
ReproSil-Pur 60 Si, 5 µm r05.04.
ReproSil-Pur 60 ODS-3

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info@dr-maisch.com +49 7073 5035 7

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