ReproSil Saphir 100 C4 from Dr. Maisch HPLC GmbH is a high-purity silica-based HPLC column with a 100 Å pore size and a butyl bonded phase. The short alkyl chain provides reduced hydrophobic retention compared to C18 and C8, allowing mild elution conditions that help preserve the structural integrity of peptides, small proteins, and other sensitive biomolecules. The ultra-pure silica base ensures high efficiency, excellent peak symmetry, and reproducible performance in both analytical and method development workflows.
ReproSil Saphir 100 C4 columns from Dr. Maisch HPLC GmbH deliver gentle yet highly efficient separations – the ideal choice for sensitive biomolecule chromatography in reversed-phase HPLC.
Fully porous, ultra-pure silica with 100 Å pore size
C4 bonding – USP L26 classification
Lower hydrophobic retention for gentle biomolecule analysis
Excellent reproducibility and peak symmetry
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm and 10 µm particle sizes
Peptide and small protein separations under mild conditions
Biopharmaceutical QC and proteomics workflows
Gradient HPLC of hydrophobic biomolecules with reduced retention
Method development for sensitive analytes
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 400 m²/g |
| Phase/Modification | C4 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 8 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil Saphir 100 C4, 5 µm | ra15.4e. |
| ReproSil Saphir 100 C4, 10 µm | ra10.4e. |