ReproSil Star SCX

Strong Cation Exchange Phase for Pharmaceutical and Biotechnical Applications

ReproSil Star SCX is a silica-based HPLC column functionalized with strong cation exchange (SCX) groups, designed for high-resolution separation of positively charged analytes in pharmaceutical and biotechnical applications. The sulfonic acid functionality provides permanent negative charges, enabling strong and selective interactions with basic compounds such as amines, peptides, and proteins.

The phase is built on high-purity, mechanically stable silica, ensuring excellent efficiency, reproducibility, and column lifetime even under demanding buffer and gradient conditions. ReproSil Star SCX offers reliable retention control, sharp peak shapes, and robust performance, making it a versatile choice for both analytical and preparative ion exchange separations.

ReproSil Star SCX columns from Dr. Maisch HPLC GmbH deliver robust, high-resolution cation-exchange performance – the optimal choice for basic compound analysis in HPLC.

Key Features:

  • Fully porous, ultra-pure silica with strong cation exchange functionality

  • Sulfonic acid groups for strong retention of cationic analytes

  • High efficiency, resolution, and peak symmetry

  • Suitable for isocratic and gradient ion-exchange methods

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Analysis of basic pharmaceuticals and metabolites

  • Separation of amino acids, peptides, and biogenic amines

  • Environmental testing for cationic contaminants

  • Method development for strong cation-exchange chromatography

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 200 Å
Phase/Modification Benzyl-SCX
Particle Type
Separation Mode
USP Code
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil Star SCX, 5 µm star5.scx.
ReproSil Star SB-C18 ReproSil Star Si

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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