ReproSil-XR 120 C4

Short-Chain C4 Column for Sensitive Biomolecule Separations

ReproSil-XR 120 C4 from Dr. Maisch HPLC GmbH is a high-purity silica-based HPLC column with a 120 Å pore size and a butyl bonded phase. The short alkyl chain provides lower hydrophobic retention compared to C18 or C8, enabling milder elution conditions that help preserve the structure and activity of peptides, small proteins, and other sensitive biomolecules. With its combination of excellent peak symmetry, high efficiency, and batch-to-batch reproducibility, this column is an excellent choice for analytical and semi-preparative workflows in life science applications.

ReproSil-XR 120 C4 columns from Dr. Maisch HPLC GmbH deliver gentle yet highly efficient separations – the ideal choice for biomolecule analysis in reversed-phase HPLC.

Key Features:

  • Fully porous, ultra-pure silica with 120 Å pore size

  • C4 bonding – USP L26 classification

  • Lower hydrophobic retention for gentle biomolecule analysis

  • Excellent reproducibility and peak shapes

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 3 µm, 5 µm, and 10 µm particle sizes

Typical Applications:

  • Peptide and small protein separations

  • Biopharmaceutical quality control

  • Gradient HPLC of hydrophobic biomolecules under mild conditions

  • Method development for sensitive analytes

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 120 Å
Surface Area 250 m²/g
Phase/Modification C4
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 5 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil-XR 120 C4, 3 µm rx13.4e
ReproSil-XR 120 C4, 5 µm rx15.4e.
ReproSil-XR 120 C4, 10 µm rx10.4e
ReproSil-XR 120 C2 ReproSil-XR 120 C8

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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