ReproSil 100 C8-AB

Acid-Base Stable C8 Column for Robust and Reproducible HPLC

ReproSil 100 C8-AB from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 100 Å pore size and an acid-base stable octyl bonded phase. This bonding technology provides extended pH stability, higher carbon content and long column lifetime, ensuring reproducible retention and excellent peak shapes even under acidic or basic mobile phase conditions. With its moderate hydrophobic retention, ReproSil 100 C8-AB is ideal for analytes that require faster elution than on C18 phases, while maintaining robust selectivity and high resolution.

ReproSil 100 C8-AB columns from Dr. Maisch HPLC GmbH combine pH stability with balanced C8 retention – the reliable choice for robust reversed-phase HPLC.

Key Features:

  • Fully porous, ultra-pure silica with 100 Å pore size

  • Acid-base stable C8 bonding – USP L7 classification

  • Wide pH range tolerance for challenging applications

  • Balanced retention and excellent peak symmetry

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • Stability-indicating assays for pharmaceutical compounds

  • Gradient and isocratic methods under varied pH conditions

  • Method development with moderate hydrophobicity requirements

  • QC and regulated testing in pharma, food, and environmental labs

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 100 Å
Surface Area 210 m²/g
Phase/Modification C8
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 12 %
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil 100 C8-AB, 5 µm r15.8b.
ReproSil 100 C8 ReproSil 100 C18

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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