ReproSil 300 SAX

Wide-Pore Strong Anion Exchange Column for Biomolecule Separations

ReproSil 300 SAX from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a 300 Å pore size and a strong anion exchange bonded phase based on quaternary ammonium functional groups. This phase provides strong ionic interactions for the retention and separation of negatively charged biomolecules, including proteins, nucleic acids, and glycoproteins. The wide-pore structure allows efficient mass transfer and accessibility for large biomolecules, ensuring high resolution, sharp peak shapes, and reproducible retention in both analytical and preparative workflows.

ReproSil 300 SAX columns from Dr. Maisch HPLC GmbH deliver robust and selective wide-pore anion exchange performance – the ideal choice for biomolecule chromatography in HPLC.

Key Features:

  • Fully porous, ultra-pure silica with 300 Å pore size

  • Strong anion exchange functionality (quaternary ammonium groups)

  • Optimized for proteins, nucleic acids, and other large biomolecules

  • High resolution and reproducibility for large-molecule ion exchange

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • Protein and glycoprotein analysis in biopharmaceutical QC

  • Nucleic acid purification and separation

  • Ion-exchange chromatography of large biomolecules

  • Method development for charged macromolecules

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 300 Å
Surface Area 100 m²/g
Phase/Modification Propyl-SAX
Particle Type
Separation Mode
USP Code
Endcapping No
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil 300 SAX, 5 µm r35.sax.
ReproSil 300 Polyamin ReproSil-PAH-EPA

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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