ReproSil 70 SCX

Strong Cation Exchange Column for Small Molecule Analysis

ReproSil 70 SCX is an ion-exchange HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica (70 Å pore size) functionalized with sulfonic acid (–SO₃H) groups. This modification provides strong cation exchange (SCX) properties, enabling robust and selective retention of basic and positively charged analytes, particularly small molecules, amines, alkaloids, and cationic metabolites. The 70 Å pore size makes this phase especially suitable for low-molecular-weight analytes, while the strong cation-exchange functionality ensures high capacity, reproducible retention, and stable performance in aqueous buffer systems.

ReproSil 70 SCX from Dr. Maisch HPLC GmbH delivers strong ion-exchange performance with high reproducibility – the ideal column for laboratories focused on small-molecule analysis and basic compound separations.

Key Features:

  • Strong cation exchange phase with sulfonic acid groups – USP L9

  • 70 Å pore size optimized for small molecules

  • High capacity and selectivity for basic and cationic analytes

  • Fully porous, high-purity spherical silica for reproducibility

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm and 10 µm particle sizes

Typical Applications:

  • Ion-exchange separations of small-molecule drugs and metabolites

  • Analysis of amines, alkaloids, and basic pharmaceuticals

  • Bioanalytical workflows involving cationic metabolites

  • Method development in pharmaceutical and chemical research

Specifications

Request Product
Particle Sizes
  • 5 µm
  • 10 µm
Pore Size 70 Å
Surface Area 500 m²/g
Phase/Modification SCX
Particle Type
Separation Mode
USP Code
Endcapping No
Carbonload 20 %
pH Range 2 - 8

Material Numbers

Phase Material Number
ReproSil 70 SCX, 5 µm r05.scx.
ReproSil 70 SCX, 10 µm r10.scx.
ReproSil 70 Phenyl ReproSil 70 Si

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us