ReproSil 80 C1

Short-Chain C1 Column for Minimal Hydrophobic Retention in Small-Molecule HPLC

ReproSil 80 C1 from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with an 80 Å pore size and a trimethylsilyl bonded phase. The short alkyl chain provides minimal hydrophobic retention, making this phase ideal for the fast elution of highly hydrophobic compounds and for use in specialized applications such as size exclusion in organic mode. The 80 Å pore size ensures high surface area and excellent efficiency for small-molecule separations, while the reduced retention allows unique selectivity in method development.

ReproSil 80 C1 columns from Dr. Maisch HPLC GmbH deliver minimal hydrophobicity with high efficiency – the ideal choice for fast and specialized small-molecule HPLC separations.

Key Features:

  • Fully porous, ultra-pure silica with 80 Å pore size

  • C1 bonding – USP L13 classification

  • Minimal hydrophobic retention for fast elution

  • High efficiency for small-molecule analysis

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Fast elution of highly hydrophobic small molecules

  • Size exclusion in organic solvent systems

  • Method development for minimal hydrophobic interaction

  • Specialized applications in pharmaceutical and chemical analysis

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 80 Å
Surface Area 220 m²/g
Phase/Modification C1
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 3 %
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil 80 C1, 5 µm r05.10.
ReproSil 80 C8

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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