ReproSil 80 Diol

Polar Diol Column for Normal-Phase and HILIC Small-Molecule Separations

ReproSil 80 Diol from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with an 80 Å pore size and a diol-functionalized bonded phase. This stationary phase offers moderate polarity and hydrogen bonding capability, making it ideal for normal-phase chromatography and hydrophilic interaction chromatography (HILIC) of small molecules. The 80 Å pore size provides a high surface area, enabling sharp peaks, high resolution, and reproducible retention for polar compounds and small analytes.

ReproSil 80 Diol columns from Dr. Maisch HPLC GmbH deliver precise and reproducible polar separations – the preferred choice for normal-phase and HILIC small-molecule chromatography.

Key Features:

  • Fully porous, ultra-pure silica with 80 Å pore size

  • Diol functionalization for controlled polar interactions

  • Suitable for normal-phase and HILIC applications

  • High efficiency for small-molecule separations

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm

Typical Applications:

  • Separation of carbohydrates and sugar alcohols

  • Polar small-molecule analysis in HILIC mode

  • Normal-phase analysis of polar natural products

  • Method development requiring moderate polar selectivity

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 80 Å
Surface Area 220 m²/g
Phase/Modification Diol
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 0 %
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil 80 Diol, 5 µm r05.d0.
ReproSil 80 CN ReproSil 80 Hexyl (C6)

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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