ReproSil OPA is a specialized reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-pure, fully porous spherical silica functionalized with C18 ligands. This column is specifically optimized for the separation of amino acids derivatized with ortho-phthalaldehyde (OPA). The bonded phase provides strong hydrophobic retention combined with excellent peak symmetry and resolution, ensuring reliable separation of amino acid derivatives in both gradient and isocratic methods. Due to its optimized selectivity and surface chemistry, ReproSil OPA is widely used in bioanalytical laboratories, clinical chemistry, and pharmaceutical quality control for reproducible amino acid profiling.
ReproSil OPA from Dr. Maisch HPLC GmbH provides high-performance reversed-phase selectivity – the ideal column for laboratories analyzing OPA-derivatized amino acids with precision and reproducibility.
C18 reversed-phase silica optimized for OPA-derivatized amino acids – USP L1
Excellent peak symmetry and reproducibility for sensitive bioanalysis
High efficiency for separating complex amino acid mixtures
Fully porous, high-purity spherical silica for robust performance
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 3 µm and 5 µm particle sizes
Separation and quantification of OPA-derivatized amino acids
Clinical and diagnostic amino acid analysis
Bioanalytical and pharmaceutical quality control
Method development for sensitive amino acid profiling
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Surface Area | 220 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 18 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil OPA, 3 µm | r13.opa. |
| ReproSil OPA, 5 µm | r15.opa. |