Ultrasep ES 100 RP8e

Endcapped C8 Column for Robust and Reproducible HPLC

Ultrasep ES 100 RP8e is a silica-based HPLC column with a 100 Å pore size and an endcapped octyl (C8) bonded phase. The endcapping process minimizes residual silanol activity, ensuring improved peak symmetry and enhanced reproducibility, especially for basic and polar analytes.

With its moderate hydrophobic retention and faster elution compared to C18 phases, RP8e is an excellent choice for analytes that are strongly retained on longer alkyl chains, while still maintaining high efficiency and column stability.

Ultrasep ES 100 RP8e combines balanced hydrophobic retention, reduced silanol interactions, and reproducible performance – the reliable choice for robust reversed-phase HPLC separations.

Key Features:

  • Silica-based stationary phase with 100 Å pore size

  • Endcapped octyl (C8) bonded phase – USP L7 classification

  • Balanced hydrophobic retention with reduced silanol activity

  • Improved peak shapes for polar and basic compounds

  • High reproducibility and column durability

  • Available particle sizes: 3 µm, 5 µm

Typical Applications:

  • Pharmaceutical impurity profiling and drug analysis

  • Separation of polar and basic analytes with sharp peak shapes

  • Environmental and food testing of moderately hydrophobic compounds

  • Method development requiring balanced retention and reproducibility

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 100 Å
Particle Type
Separation Mode
USP Code
Endcapping Yes
pH Range 2 - 8

Material Numbers

Phase Material Number
Ultrasep ES 100 RP8e, 3 µm u13.8e.
Ultrasep ES 100 RP8e, 5 µm u15.8e.
Ultrasep ES 100 RP8 Ultrasep ES 100 RP18

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info@dr-maisch.com +49 7073 5035 7

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