Ultrasep ES Pharm Spezial RP18e

Endcapped Specialty C18 HPLC Column for Pharmaceutical Applications

Ultrasep ES Pharm-Spezial RP18e is a silica-based HPLC column with an endcapped specialty C18 bonded phase, engineered to combine strong hydrophobic retention with minimized silanol activity. The advanced endcapping process reduces secondary interactions, ensuring sharper peak shapes and higher reproducibility, especially for basic and polar compounds.

The “Spezial” bonding chemistry enhances robustness and long-term stability, making this column suitable for demanding pharmaceutical applications such as impurity profiling, stability-indicating assays, and regulatory testing. With particle size options of 5 µm and 7 µm, Pharm-Spezial RP18e provides flexibility for both routine quality control and advanced analytical workflows.

Ultrasep ES Pharm-Spezial RP18e combines the benefits of endcapping and specialty C18 bonding – the reliable choice for pharmaceutical laboratories requiring reproducible and long-lasting HPLC separations.

Key Features:

  • Silica-based stationary phase with endcapped specialty C18 chemistry

  • Reduced silanol activity for improved peak symmetry

  • Strong hydrophobic retention with robust reproducibility

  • Specialty bonding ensures long operational lifetime

  • Available particle sizes: 5 µm, 7 µm

Typical Applications:

  • Pharmaceutical impurity profiling and stability testing

  • Analysis of basic and polar drugs with improved peak shapes

  • Routine quality control and regulatory compliance testing

  • Method development requiring robust and reproducible C18 selectivity

Specifications

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Particle Sizes
  • 5 µm
  • 7 µm
Pore Size 100 Å
Particle Type
Separation Mode
USP Code
Endcapping Yes
pH Range 2 - 8

Material Numbers

Phase Material Number
Ultrasep ES Pharm Spezial RP18e, 5 µm u15.ps9e.
Ultrasep ES Pharm Spezial RP18e, 7 µm u17.ps9e.
Ultrasep ES Pharm Spezial RP18 Ultrasep ES Phen (ol)

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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