Ultrasep ES Pharm-Spezial RP8e

Endcapped Specialty C8 HPLC Column for Pharmaceutical Analysis

Ultrasep ES Pharm-Spezial RP8e is a silica-based HPLC column with an endcapped specialty C8 bonded phase, engineered for pharmaceutical applications that require balanced hydrophobicity and minimized silanol interactions. The endcapping process reduces residual silanol activity, resulting in sharper peak shapes and improved reproducibility, particularly for basic and polar analytes.

Compared to conventional C18 phases, the shorter C8 chains deliver faster elution and enhanced resolution for moderately hydrophobic compounds. The “Spezial” bonding chemistry ensures robustness, long lifetime, and reproducibility, making Pharm-Spezial RP8e ideal for pharmaceutical quality control and method development.

Ultrasep ES Pharm-Spezial RP8e combines specialty bonding with endcapping technology – the reliable choice for pharmaceutical laboratories seeking reproducible and efficient C8 separations.

Key Features:

  • Silica-based stationary phase with endcapped specialty C8 bonded chemistry

  • Reduced silanol activity for improved peak symmetry

  • Balanced hydrophobic retention with faster elution than C18

  • High reproducibility and robust column lifetime

  • Available particle size: 5 µm

Typical Applications:

  • Pharmaceutical impurity profiling and stability-indicating assays

  • Analysis of basic and polar drugs with improved peak shapes

  • Routine quality control in pharmaceutical production

  • Method development requiring robust and reproducible C8 selectivity

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 100 Å
Particle Type
Separation Mode
USP Code
Endcapping Yes
pH Range 2 - 8

Material Number

Phase Material Number
Ultrasep ES Pharm-Spezial RP8e, 5 µm u15.ps8e.
Ultrasep ES Pharm-Spezial RP8 Ultrasep ES Pharm Spezial RP18

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info@dr-maisch.com +49 7073 5035 7

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