Ultrasep ES Phenyl-SCX75

Strong Cation Exchange Phenyl HPLC Column

Ultrasep ES Phenyl-SCX75 is a silica-based HPLC column combining phenyl bonded chemistry with strong cation exchange (SCX) functionality. This dual interaction mechanism provides both π–π aromatic selectivity and ionic retention, making it highly effective for the separation of basic and cationic analytes, including pharmaceuticals, peptides, and metabolites.

The SCX75 phase offers robust performance, sharp peak shapes, and reproducibility under demanding analytical conditions. Its combination of phenyl and cation exchange interactions enables orthogonal selectivity compared to conventional reversed-phase or ion exchange columns, making it an excellent tool for method development and complex mixture analysis.

Ultrasep ES Phenyl-SCX75 delivers powerful dual-mode selectivity – the reliable choice for laboratories analyzing basic, cationic, and aromatic compounds in HPLC.

Key Features:

  • Silica-based stationary phase with phenyl and strong cation exchange (SCX) chemistry

  • Dual interaction mechanism: π–π aromatic and ionic retention

  • Enhanced selectivity for basic and cationic analytes

  • Robust bonding for reproducibility and long column lifetime

  • Available particle size: 5 µm

Typical Applications:

  • Separation of basic pharmaceuticals and metabolites

  • Peptide and protein fragment analysis with cation exchange selectivity

  • Environmental monitoring of cationic pollutants

  • Method development requiring complementary SCX and phenyl interactions

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 100 Å
Particle Type
Separation Mode
USP Codes
pH Range 2 - 8

Applications

Material Number

Phase Material Number
Ultrasep ES Phenyl-SCX75, 5 µm u15.scx7.
Ultrasep ES Phenoxycarb Ultrasep ES RP8F

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