Adsorbosil Si

Unmodified Silica Phase for Classical Normal-Phase HPLC

Adsorbosil Si is a pure, unmodified silica phase optimized for traditional normal-phase HPLC applications. Its high surface area and controlled pore structure provide excellent retention of polar analytes when using non-polar mobile phases such as hexane, heptane, or iso-octane in combination with polar modifiers (e.g. ethyl acetate, isopropanol).

Thanks to its polar silanol groups, Adsorbosil Si offers strong hydrogen bonding and dipole-dipole interactions, making it particularly well-suited for the separation of positional isomers, stereoisomers, and other structurally similar compounds.

Adsorbosil Si is a dependable column for classical normal-phase separations where unmodified silica interaction is essential for selectivity and resolution.

Adsorbosil Si is a good alternative to Polygosil® Si.

Key Features

  • High-purity, unbonded silica – ideal for normal-phase mode

  • Strong silanol activity for polar compound retention

  • Excellent peak shape and reproducibility

  • Compatible with standard non-polar mobile phases

  • Particle sizes typically 5 µm, 7 µm and 10 µm

  • Also used as base material for custom bonding or derivatization

Typical Applications

  • Separation of structural isomers and enantiomers (non-chiral mode)

  • Analysis of steroids, lipids, and neutral organics

  • Normal-phase flash chromatography setups

  • Precursor for customer-specific surface modifications

Specifications

Request Product
Particle Sizes
  • 5 µm
  • 7 µm
  • 10 µm
Pore Size 60 Å
Surface Area 350 m²/g
Phase/Modification Si
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 0 %
pH Range 2 - 8

Material Numbers

Phase Material Number
Adsorbosil Si, 5 µm 5201038.
Adsorbosil Si, 7 µm 5201041.
Adsorbosil Si, 10 µm 5201039.
Adsorbosil NH2

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