Adsorbosil NH2

Aminopropyl-Modified Silica Phase for HILIC, Normal Phase, and Sugar Analysis

Adsorbosil NH2 is a versatile aminopropyl-modified (NH₂) silica phase designed for multiple chromatographic modes including normal-phase, HILIC, and specialized carbohydrate analysis. The polar amino functionality allows strong dipole interactions, making this phase ideal for separating hydrophilic and weakly basic compounds.

In normal-phase mode, Adsorbosil NH2 provides retention for polar compounds using non-polar eluents such as heptane. In reversed-phase or HILIC mode, it is well-suited for sugars, sugar alcohols, and other small polar molecules using acetonitrile-water or methanol-water mixtures.

Adsorbosil NH2 is a powerful tool for specialized analytical tasks requiring polar retention, HILIC functionality, or carbohydrate-specific selectivity.

Adsorbosil NH2 is a good alternative to Polygosil® NH2.

Key Features

  • Aminopropyl (NH₂) bonded phase – USP L8 classification

  • Suitable for HILIC, normal-phase, and reversed-phase (limited) applications

  • Ideal for sugar and carbohydrate separations

  • Fully porous, high-purity silica base

  • Stable under neutral and slightly alkaline pH conditions

  • Available in standard particle sizes (5 µm and 10 µm)

Typical Applications

  • Monosaccharide and oligosaccharide analysis

  • Sugar alcohols and organic acids

  • Hydrophilic pharmaceuticals and excipients

  • Polar pesticide and herbicide screening

  • Normal-phase separations of polar compounds

Specifications

Request Product
Particle Sizes
  • 5 µm
  • 10 µm
Pore Size 60 Å
Surface Area 350 m²/g
Phase/Modification NH2
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 3 %
pH Range 2 - 8

Material Numbers

Phase Material Number
Adsorbosil NH2, 5 µm 5201036.
Adsorbosil NH2, 10 µm 5201037.
Adsorbosil CN Adsorbosil Si

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