Adsorbosphere XL C8 is a reversed-phase HPLC column based on high-purity, fully porous silica, modified with octyl (C8) groups and treated with advanced extended-lifetime surface chemistry. Designed for routine and regulated use, this column combines medium hydrophobic retention with enhanced stability and superior column lifetime — making it ideal for long-term reversed-phase applications.
Compared to C18, Adsorbosphere XL C8 offers faster elution for hydrophobic compounds and improved performance for moderately polar analytes. Its optimized endcapping ensures excellent peak shapes, even for basic compounds, over extended usage.
Adsorbosphere XL C8 delivers reliable reversed-phase performance and extended stability — perfect for high-volume labs that require robust, long-lasting C8 selectivity.
C8-bonded silica (USP L7) with extended-lifetime bonding
Moderate hydrophobicity for faster retention vs. C18
Enhanced endcapping for improved peak shape and pH stability
Excellent durability for high-throughput and routine analysis
Fully porous silica with high reproducibility
Available in 3 µm, 5 µm and 10 µm particle sizes
Routine QC of APIs, drug formulations, and metabolites
Faster separations of hydrophobic compounds
Basic analytes requiring low tailing and long column life
Food, cosmetic, and chemical product screening
Method transfer and validation in regulated environments
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 11 % |
| Phase | Material Number |
|---|---|
| Adsorbosphere XL C8, 3 µm | 5200054 |
| Adsorbosphere XL C8, 5 µm | 5200055 |
| Adsorbosphere XL C8, 10 µm | 5200056 |