EcoPrep 120 C18-2 HE

High-Efficiency Preparative C18 Column for Small Molecule Purification

EcoPrep 120 C18-2 HE is a preparative HPLC column packed with high-purity, fully porous silica featuring a 120 Å pore size and bonded with a high-efficiency C18 (octadecyl) phase. Designed for the purification of small to medium-sized molecules, this column delivers strong hydrophobic retention, excellent loading capacity, and reliable peak shape for compound isolation in pharmaceutical and chemical production environments.

EcoPrep 120 C18-2 HE delivers high-efficiency preparative performance – ideal for small molecule workflows requiring reproducibility, resolution, and scalability.

Key Features

  • C18-bonded silica with 120 Å pores and high surface area

  • Optimized for high-efficiency preparative separations

  • Strong hydrophobic retention for non-polar compounds

  • Fully porous silica with robust mechanical stability

  • Available in preparative dimensions and 10 µm particle size

Typical Applications

  • Preparative purification of APIs and pharmaceutical intermediates

  • Compound isolation for research or pilot-scale production

  • Fractionation of natural products and chemical libraries

  • Cost-effective scale-up from analytical to preparative methods

Specifications

Request Product
Particle Sizes
  • 10 µm
  • 20 µm
  • 30 µm
  • 50 µm
Pore Size 120 Å
Surface Area 320 m²/g
Phase/Modification C18
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 27 %
pH Range 2 to 8

Material Numbers

Phase Material Number
EcoPrep 120 C18-2 HE, 10 µm 6136886
EcoPrep 120 C18-2 HE, 20 µm 6136887
EcoPrep 120 C18-2 HE, 30 µm 6136888
EcoPrep 120 C18-2 HE, 50 µm 6136889
EcoPrep 120 C18-2 NE

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info@dr-maisch.com +49 7073 5035 7

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