Equisorb CN is a cyanopropyl-modified HPLC column based on fully porous, high-purity silica, designed for use in both normal-phase and reversed-phase chromatography. The polar CN group enables dipole-dipole interactions and provides moderate hydrophobic retention, making this column ideal for the separation of polar, aromatic, or structurally similar analytes that may be challenging to resolve on conventional alkyl phases. Equisorb CN offers flexibility, cost-efficiency, and reliable performance for routine method development and analytical applications.
Equisorb CN delivers reliable dual-mode selectivity and polar retention – an excellent choice for versatile HPLC separations in routine and exploratory workflows.
Cyanopropyl (CN) bonded phase – USP L10 classification
Dual-mode selectivity: supports both normal-phase and reversed-phase HPLC
Polar interactions for aromatic and moderately polar compounds
Fully porous silica for stable, reproducible retention behavior
Available in 3 µm, 5 µm and 10 µm particle sizes
Polar pharmaceuticals and aromatic drug substances
Isomer separations and selectivity screening
Normal-phase separations of neutral organics
Cost-effective reversed-phase method development
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Surface Area | 220 m²/g |
| Phase/Modification | CN |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| Carbonload | 7.5 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Equisorb CN, 3 µm | e03.c0. |
| Equisorb CN, 5 µm | e05.c0. |
| Equisorb CN, 10 µm | e00.c0. |