Equisorb C8

Reversed-Phase HPLC Column with Moderate Hydrophobic Retention

Equisorb C8 is a reversed-phase HPLC column packed with fully porous, high-purity silica particles bonded with octyl groups. This medium-chain alkyl phase provides moderate hydrophobic retention, offering shorter analysis times compared to C18 columns while maintaining good selectivity and resolution. Equisorb C8 is well suited for compounds that elute too strongly on C18 and is ideal for routine quality control, method development, and the analysis of moderately non-polar analytes.

Equisorb C8 offers reliable and efficient chromatographic performance – ideal for reversed-phase HPLC workflows requiring reduced retention and robust peak shape.

Key Features:

  • Octyl (C8) bonded silica – USP L7

  • Moderate hydrophobic retention for mid-polarity compounds

  • Suitable for gradient and isocratic reversed-phase separations

  • Fully porous, high-purity silica with consistent performance

  • Compatible with a wide range of mobile phase systems

  • Available in 3 µm, 5 µm and 10 µm particle sizes

Typical Applications:

  • Routine HPLC of pharmaceuticals, chemicals, and excipients

  • Method development requiring shorter retention than C18

  • Separation of moderately hydrophobic compounds

  • General-purpose reversed-phase chromatography

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 80 Å
Surface Area 220 m²/g
Phase/Modification C8
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 11.5 %

Material Numbers

Phase Material Number
Equisorb C8, 3 µm e03.8e.
Equisorb C8, 5 µm e05.8e.
Equisorb C8, 10 µm e00.8e.
Equisorb C6 Equisorb CN

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