Exsil 100 Amino is an aminopropyl-modified silica-based HPLC stationary phase built on high-purity Exsil 100 silica with a nominal pore size of 100 Å. The bonded amino functionality provides polar and weak anion-exchange characteristics, enabling versatile selectivity for a broad range of polar and ionic compounds.
Due to its dual retention behavior, Exsil 100 Amino can be operated in normal-phase HPLC, HILIC-type separations, and weak anion-exchange modes. This makes the phase particularly suitable for the separation of carbohydrates, sugars, organic acids, and other highly polar analytes that are poorly retained on conventional reversed-phase materials.
The controlled silica synthesis and stable aminopropyl bonding ensure reproducible retention, consistent selectivity, and reliable performance in both routine analytical applications and method development.
Exsil 100 Amino offers versatile selectivity and reliable performance for challenging polar separations, making it a robust choice for normal-phase, HILIC, and ion-exchange HPLC applications.
• Aminopropyl-modified silica-based HPLC phase
• 100 Å pore size optimized for small and medium molecular weight analytes
• Polar and weak anion-exchange retention mechanisms
• Suitable for normal-phase, HILIC-type, and ion-exchange separations
• Good retention of highly polar and ionic compounds
• High batch-to-batch reproducibility
• Suitable for analytical and preparative HPLC
• Particle sizes available in: 1.5 µm, 3 µm, 5 µm, 10 µm
• Normal-phase HPLC of polar organic compounds
• HILIC-type separations of carbohydrates and sugars
• Separation of organic acids and small ionic molecules
• Analysis of polar metabolites and intermediates
• Method development and routine QC in pharmaceutical, chemical, food, and environmental analysis
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | NH2 |
| Particle Type | |
| Separation Modes | |
| USP Code |
| Phase | Material Number |
|---|---|
| Exsil 100 Amino, 1.5 µm | 5136657. |
| Exsil 100 Amino, 3 µm | 5136655. |
| Exsil 100 Amino, 5 µm | 5136658. |
| Exsil 100 Amino, 10 µm | 5136659. |