Exsil 100 Si is a bare, unmodified silica-based HPLC stationary phase based on high-purity Exsil 100 silica with a nominal pore size of 100 Å. The exposed silanol surface provides strong polar interactions, making the phase highly suitable for adsorption and normal-phase HPLC separations.
Due to its high surface activity and pronounced polarity, Exsil 100 Si enables efficient retention and separation of polar compounds through hydrogen bonding, dipole–dipole, and adsorption mechanisms. The phase is commonly used as a reference material in method development and for applications where strong polar selectivity is required.
Controlled silica synthesis and narrow particle size distribution ensure reproducible retention behavior, consistent selectivity, and robust chromatographic performance in both routine analysis and method development.
Exsil 100 Si provides strong polar selectivity and reliable performance, making it a fundamental stationary phase for normal-phase and adsorption-based HPLC separations of small molecules.
• Bare silica-based HPLC phase with exposed silanol surface
• 100 Å pore size optimized for small and medium molecular weight analytes
• Strong polar retention via adsorption mechanisms
• Suitable for normal-phase HPLC separations
• High surface activity for polar compound retention
• Reproducible retention and stable selectivity
• High batch-to-batch reproducibility
• Suitable for analytical and preparative HPLC
• Particle sizes available in: 1.5 µm, 3 µm, 4 µm, 5 µm, 10 µm
• Normal-phase HPLC of polar organic compounds
• Adsorption chromatography of small molecules
• Separation of isomers and structurally related polar compounds
• Method development and selectivity screening
• Routine QC in pharmaceutical, chemical, and analytical laboratories
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | Si |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| Carbonload | 0 % |
| Phase | Material Number |
|---|---|
| Exsil 100 Si, 1.5 µm | 5136656. |
| Exsil 100 Si, 3 µm | 5136510. |
| Exsil 100 Si, 4 µm | 6136972. |
| Exsil 100 Si, 5 µm | 5136522. |
| Exsil 100 Si, 10 µm | 5136541. |