Exsil 100 SH is a shape-selective reversed-phase HPLC stationary phase based on high-purity Exsil 100 silica with a nominal pore size of 100 Å. The SH (Shape) surface chemistry is designed to emphasize steric and geometric interactions in addition to hydrophobic retention, enabling enhanced discrimination of structurally related compounds.
The shape-selective character of Exsil 100 SH makes it particularly effective for the separation of positional isomers, stereoisomers, and structurally similar small molecules that are difficult to resolve on conventional reversed-phase materials. The phase provides controlled retention, improved selectivity, and reproducible chromatographic behavior in demanding separations.
Controlled silica synthesis and stable surface modification ensure excellent batch-to-batch reproducibility, consistent selectivity, and robust performance in both routine analysis and advanced method development.
Exsil 100 SH delivers enhanced shape-based selectivity and reliable performance, making it a powerful complementary reversed-phase option for challenging small-molecule HPLC separations where conventional phases provide insufficient resolution.
• Shape-selective reversed-phase silica-based HPLC phase
• 100 Å pore size optimized for small and medium molecular weight analytes
• Enhanced steric and geometric selectivity
• Improved resolution of structurally related compounds
• Complementary selectivity to conventional C8 and C18 phases
• Reproducible retention and stable chromatographic behavior
• High batch-to-batch reproducibility
• Suitable for analytical and preparative HPLC
• Particle size available in: 10 µm
• Reversed-phase HPLC of structural and positional isomers
• Separation of stereoisomers and closely related analogues
• Analysis of pharmaceutical APIs with subtle structural differences
• Selectivity optimization in method development
• Routine QC and advanced separations in pharmaceutical, chemical, and analytical laboratories
| Particle Size |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | SH |
| Particle Type | |
| Separation Mode |
| Phase | Material Number |
|---|---|
| Exsil 100 SH, 10 µm | 6136950. |