Exsil 80 C1 (TMS) is a silica-based HPLC stationary phase with an 80 Å pore size and a trimethylsilyl (C1, TMS) bonded surface. The very short alkyl chain provides minimal hydrophobic retention, enabling fast elution and high efficiency for analytes that are excessively retained on longer alkyl phases such as C8 or C18.
The controlled pore structure offers a high surface area, supporting sharp peak shapes and reproducible retention behavior in small-molecule separations. Exsil 80 C1 (TMS) is particularly useful for high-throughput methods, early-eluting compounds, and applications requiring reduced retention strength in reversed-phase HPLC.
Exsil 80 C1 (TMS) provides controlled low retention, high efficiency, and reproducible performance, making it an effective solution for fast and selective reversed-phase HPLC separations.
Silica-based HPLC stationary phase with 80 Å pore size
Trimethylsilyl (C1, TMS) bonded phase
Very low hydrophobic retention for fast separations
High efficiency and reproducible chromatographic performance
Suitable for small-molecule reversed-phase HPLC
Available particle sizes: 3 µm, 5 µm
Fast reversed-phase separations of small molecules
Analysis of compounds strongly retained on C8 or C18 phases
High-throughput pharmaceutical screening
Method development requiring minimal hydrophobic retention
Environmental and chemical analysis of early-eluting analytes
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Surface Area | 220 m²/g |
| Phase/Modification | C1 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Exsil 80 C1 (TMS), 3 µm | 5136654. |
| Exsil 80 C1 (TMS), 5 µm | 5136493. |